• FREE WEBINAR: Let your Primary Cells be in the SPA-Oasis

    PELOBIOTECH. Join your FREE WEBINAR. How to Develop and Optimize your Media/Wie im Paradies: Medienentwicklung und –optimierung für Primäre Zellen

     

    1. Tue, 26. April 2016, 15:00 – 16:00 MESZ

    presented by Lothar Steeb, PhD, CSO, PELOBIOTECH

    Please share this Information with your co-workers and friends. Thank you.

    Your PELOBiotech-Team

    weiter Lesen
  • Flawed Mitochondrial DNA Could Undermine Stem Cell Therapies

    Mutations in our mitochondrial DNA tend to be inconspicuous, but they can become more prevalent as we age. They can even vary in frequency from cell to cell. Naturally, some cells will be relatively compromised because they happen to have a higher percentage of mutated mitochondrial DNA. Such cells make a poor basis for stem cell lines. They should be excluded. But how?

    To read Details, click here

    weiter Lesen
  • Damaging Consequences of Zika Virus Infection in Human Minibrains

    In Allgemein on

    Brazilian researchers from the D’Or Institute for Research and Education (IDOR) and Federal University of Rio de Janeiro (UFRJ) have demonstrated the harmful effects of ZIKA virus (ZIKV) in human neural stem cells, neurospheres and brain organoids. Since ZIKV has been gradually established as a direct cause of central nervous system malformations, this study help to elucidate the etiological nature of the recently increasing number of microcephaly cases in Brazil.
    To read more, please click here.

     

    weiter Lesen
  • PELOBIOTECH: MEET US AT…

    In Allgemein on

    We are on the road again: We love to meet you personally at the Hausmesse with our partners in Mainz, April 14 at Foyer Forschungshaus Mainz, block #911. You can inform yourself about hot topics of cryopreservation, brandnew media tools and procedures of genetic analyzing, future developments of digital PCR systems and our entire Primary Cell Portfolio esp. on The New Generation of 3D models. Come and meet us there!

    Where to find us: download map

    weiter Lesen
  • Co-Culture of Aortic Endothelial & Smooth Muscle Cells

    In Allgemein on

    A novel role of endothelium in activation of latent pro-membrane type 1 MMP and pro-MMP-2 in rat aorta.

    Aims Aortic stiffness is an independent risk factor for progression of cardiovascular diseases. Degradation of elastic fibres in aorta due to angiotensin II (ANGII)-stimulated overactivation of latent membrane type 1 matrix metalloproteinase (MT1MMP) and matrix metalloproteinase-2 (MMP2) is regarded to represent an important cause of aortic stiffness. Therefore, clarification of the causal mechanisms triggering the overactivation of these MMPs is of utmost importance. This study addresses the endothelium as a novel key activator of latent pro-MT1MMP and pro-MMP2 in rat aorta.

    To read more, please click to our Partner’s CA Newsletter.

    weiter Lesen
  • Retinal Ganglion Cells Derived From Pluripotent Stem

    Stepwise differentiation through an enriched retinal progenitor intermediary facilitates the accomplishment of deriving retinal ganglion cells (RGCs) from human pluripotent stem cells (hPSCs), according to Research.  Sarah K. Ohlemacher, from Indiana University-Purdue University Indianapolis, and colleagues examined the process of differentiating hPSCs to a retinal lineage and attempted to derive RGCs from hPSCs.
    To read more please click here.

    weiter Lesen
  • Using Gene Editing to Delete HIV from Human T Cells

    In Allgemein on

    Researchers at Temple University used a CRISPR gene editing technique to remove HIV from the DNA of human cells grown in culture. Their study (“Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing”) is published In Scientific Reports.

    According to senior investigator on the new study, Kamel Khalili, Ph.D., Laura H. Carnell Professor and Chair of the Department of Neuroscience, Director of the Center for Neurovirology, and Director of the Comprehensive NeuroAIDS Center at the Lewis Katz School of Medicine at Temple University (LKSOM), “Antiretroviral drugs are very good at controlling HIV infection. But patients on antiretroviral therapy who stop taking the drugs suffer a rapid rebound in HIV replication.” The presence of numerous copies of HIV weakens the immune system and eventually causes acquired immune deficiency syndrome, or AIDS.
    To read more, please click here.

    weiter Lesen
  • Removing Epigenetic Post-it Notes Returns Stem Cells to Unprimed State

    In Allgemein on

    A drug originally intended to treat leukemia has an unexpected power. It can reverse stem cell development, converting primed pluripotent stem cells to naïve pluripotent stem cells. The drug, called MM-401, effectively removes epigenetic markers from histones, depriving the cell’s DNA-reading machinery of indications of where to start reading. Stripped of its accumulated “Post-it notes,” the DNA instruction manual is like new. It lacks any indications that any sections should receive any special attention.

    To read more please click here.

    weiter Lesen
  • New Technique to Derive Naive Pluripotent Stem Cells from Human Embryos

    Researchers from the University of Cambridge have come up with a technique using which naive pluripotent stem cells from human embryos can be derived. These cells are having amazing feature that they can develop into all human tissue other than placenta.

    The promising technique could open new gateways for research into disorders like Down’s syndrome. The researchers are quite hopeful that the development could lead to advances in regenerative medicine.
    To read more, please click here.

    weiter Lesen
  • PELOBiotech: Welcome, Katja!

    In Allgemein on

    We are happy to announce that we enlarge our team and can serve you now even better.
    Katja Schulze joined our company in March and will be in charge of all customer questions in Germany and Switzerland. So go ahead and give her a call. 0049- 89- 517 286 59-0. She will be more than happy to be at your service.

    weiter Lesen
  • “Mini-Stomachs” That Produce Insulin When Transplanted

    In Allgemein on

    A team of researchers have succeeded in creating mini insulin-producing organs that can be implanted into a diabetic animal to maintain glucose levels, progress towards what they consider the future of regenerative medicine.

    The cells the researchers found are best at producing insulin when reprogrammed are pylotic cells — cells from the lower region of the stomach, called the “pylorus region.”

    They think that these cells work best because they are naturally very similar to the pancreatic beta cells that normally carry out this function. What they do better than other cells is respond to high glucose levels by producing insulin to normalize blood sugar levels.

    To read more, please click here.

    weiter Lesen
  • MEET US AT… IGLD 2016 in Hamburg

    In Allgemein on

    Feb. 25-26, 2016, Messehallen Hamburg: HAPPY BIRTHDAY IGLD

    Meet our CEO, Peter Frost, at the IGLD 2016.

    Listen to his lecture on “Magnetic Bioprinting in the field of Personalised Medicine”.

    And let us celebrate: Party till the morning and celebrate the 20th birthday of IGLD.

    weiter Lesen
  • FREE WEBINAR: A Physiological Microfluidic Platform for Cell Based Assays

    In Allgemein, Webinar on

    Join this FREE WEBINAR on Physiological Microfluidic Platform for Cell Based Assays

    date: Tue, 23 February, 2016

    time: 4:00 PM (CET)

    language: English

    presented by B. Prabhakar Pandian, Chief Technology Officer, SynVivo 

    Cell-cell interactions are critical components of many physiological and pathological conditions in the microvasculature. Similarly, particle-cell interactions play an important role in targeted delivery of therapeutics to the microcirculation. Static well plate assays and in vitro fluidic devices have been instrumental in our understanding of the biological phenomena. However, widely used parallel plate flow chambers suffer from several limitations for studying the physiological conditions in vivo. (mehr …)

    weiter Lesen
  • First Robotically driven Experimentation System Reduces Drug Discovery Costs

    In Allgemein, Cell Culture, product news on

    Researchers have created the first robotically driven experimentation system which reduces the number of necessary experiments throughout drug discovery by 70%. To read more, please click here.

     

    weiter Lesen
  • PELOBIOTECH: Here we are… at LS2

    In Allgemein on

    Welcome to the LS² Annual Meeting 2016 in Lausanne in Switzerland!

    Discover the latest, most exciting findings in the field of Chemical Biology over Synthetic Biology to Proteomics and “Classic” Molecular and Cell Biology , discuss opportunities and challenges of the Swiss Research funding system and the life beyond academia in non-academic professions. And find out more about the excting products ot

    We are happy to meet you at our Swiss Partner’s booth, abc biopply #34. To download where you can find us, please click here.

     

    weiter Lesen
  • FREE WEBINAR: Get the Click – New Assays for HTS and Alternatives for BrdU

    In Allgemein, Webinar on

    presented by Birgit Oberleitner, PhD, baseclick GmbH Germany

    By attending this webinar, you will learn about:

    • the baseclick DNA labeling technology based on click chemistry
    • a robust, more sensitive and rapid alternative to the BrdU cell proliferation assay
    • a method allowing rapid cell detection procedure without false positives
    • exciting application fields of this technique f.ex. High through put Screening (HTS)

    We are looking forward to your attendance.

    To sign up, please click on the following links:
    10 am language: German) and
    4 pm (MEZ), language: English

    Please share the information with your colleagues and friends.

    Your PELOBiotech & baseclick Team

    weiter Lesen
  • PELOBIOTECH: Meet us at… LS2

    In Allgemein on

    It´s fair time and we are thrilled to talk to you at LS2 Annual Meeting 2016 in Lausanne, Switzerland. Meet and greet our CEO, Dr. Peter Frost, at our Swiss partner abc biopply, booth #34.

    In these two days, you will hear plenary lectures from experts in other sciences, such as mathematics, physics and chemistry, whose contributions have been fundamental in advancing the life sciences. From mechanics of animal cells and tissues with D. Discher (University of Pennsylvania), and L. Mahadevan, (Harvard University), we will further explore mathematical aspects of cell organization in plant tissues and signaling networks with V. Grieneisen (John Innes Center).

    To get the final program, please click here.

    To find the floor plan, please click here.

     

    weiter Lesen

More of Pelobiotech

Cell Culture Shop